This weekend, we’ll have an exciting matchup between the Buffalo Bills, one of the season’s biggest surprises, and the San Francisco 49ers, one of the major disappointments.
The Bills are on an impressive streak and recently ended the Kansas City Chiefs’ long unbeaten run with a 30-21 victory.
Meanwhile, the 49ers are coming off two consecutive losses, drifting further away from the playoffs and the chance to return to a Super Bowl.
Buffalo Bills vs. San Francisco 49ers Betting Odds and Info
Why bet on the Buffalo Bills?
Two weeks ago, the Buffalo Bills pulled off what might be the biggest surprise of the season: defeating the Kansas City Chiefs. The reigning back-to-back NFL champions were 10-0 this season until they stumbled against Sean McDermott’s team.
The Bills secured a 30-21 victory thanks to an excellent performance by Josh Allen, who completed 27 of 40 passes for 262 passing yards, one touchdown pass, and added 55 rushing yards and a touchdown on 12 carries. The other scores came from Curtis Samuel through the air and two rushing touchdowns by James Cook.
This marks six consecutive wins for the team, which now boasts a 9-2 record, sitting second in the AFC and leading the AFC East with a significant advantage over the second-place Miami Dolphins (5-6).
One area for improvement is kicker Tyler Bass, who has missed four extra-point attempts.
Why bet on the San Francisco 49ers?
Things have not gone well for the San Francisco 49ers. After losing last year’s final to the Kansas City Chiefs, they were expected to compete for the Super Bowl title again. However, they currently sit last in the NFC West with a 5-6 record.
In their last game, they were crushed by the Green Bay Packers 38-10, marking their second consecutive loss. Among the absences that day was quarterback Brock Purdy, sidelined with a right shoulder injury. While he has been practicing this week, his availability for the weekend remains uncertain.
Key players on the injured list include Nick Bosa, Trent Williams, Aaron Banks, Jordan Elliott, Demetrius Flannigan-Fowles, and Deommodore Lenoir, highlighting significant roster challenges. Additionally, Christian McCaffrey has been resting but is not injured and should play on Sunday.
The main issue for Kyle Shanahan’s team has been scoring touchdowns. Despite boasting one of the best averages for yards per game (384.5), they have struggled to convert those into points, with their 24 touchdowns ranking among the lowest in the NFL.
Final Betting Analysis: Buffalo Bills vs. San Francisco 49ers
The last time these two teams faced off was on December 7, 2020, when the Bills won in San Francisco 24-34. The previous matchup in Buffalo took place on October 16, 2016, with the locals securing a commanding 45-16 victory.
The 49ers are on a two-game losing streak against this opponent. The last time they defeated the Bills was in 2012 with a 45-3 blowout, and the last away victory came in 2008 with a 3-10 result.
The numbers at Gambyl Exchange favor the Buffalo Bills, with a Moneyline of 1.35, while the San Francisco 49ers sit at 3.6.
The Bills are having an outstanding season and are motivated not only by their winning streak but also by ending the Chiefs’ undefeated run. They will use this momentum to their advantage as they aim to extend their record and defeat the San Francisco 49ers. Go for a victory for the locals at the OVER.
Go for a win for the Bills. If you bet $100 at 1.35, you will gain $35 for a total payout of $135.
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