Clausura MX 2025: Matchday 16 Betting Favorites

The Clausura MX 2025 of the Liga MX regular season is reaching its final moments, and teams are gearing up for a fierce battle over the three points in matchday 16.

We all know that the main objective of the teams is to get their direct ticket to the next Liguilla. However, they may also settle for a place in the Play-Ins, so everything will be defined in the next few days when they play the last two matchdays.

Right now, Toluca has risen to win many consecutive matches and thus managed to knock América off the top of the standings. However, their direct qualification is not 100% guaranteed either, considering that the difference between them and Necaxa—seventh place—is 6 points.

Likewise, it is fair to mention that the teams in the upper zone of the table will ensure their direct ticket to the next Liguilla with a win on matchday 16.

Below, we bring you the preview of the best games of this matchday 16 of the Clausura 2025 of Liga MX, with their respective betting odds and our free predictions.

Clausura MX Probabilidades e escolhas semanais de apostas

Clausura MX 2025: Matchday 16: Pachuca x Tigres

The Tuzos come into this match with two consecutive victories, one against América and the other at home over Necaxa. They are full of confidence as they prepare to face Los Felinos, also coming into the match on a positive note after defeating Monterrey in the Clasico Regio and securing a spot in the CONCACAF Champions League semifinals.

Both teams are in excellent form, setting the stage for an intense conclusion to the Liga MX season while vying for a top spot in the standings.

Pachuca recently dominated Necaxa with a 5-3 win in their previous match, taking 27 points and putting them in contention for the top spots. While their direct qualification is now out of their control, their goal is to capitalize on their home advantage against Tigres.

Meanwhile, Tigres is coming off a 2-1 victory over Rayados in the Clasico Regio, consolidating its position in the direct qualification zone. With a solid squad and a track record of success at crucial moments, the Monterrey side is determined not to lose ground as the tournament nears its exciting conclusion.

We expect a very evenly matched game, so our prediction is for a 1-1 draw on the scoreboard.

Pachuca vs. Tigres Betting Pick: Draw

Clausura MX 2025: Matchday 16: Cruz Azul vs. León

La Máquina is coming off a satisfying draw with América in the CONCACAF Champions League. However, they are in fifth place with a positive result from three consecutive matches against their direct rivals. Eager to maintain their good form and challenge for first place, they prepare to face the Beast.

On the other hand, Los Panzas Verdes are also vying for the top spot in this upcoming double header, setting the stage for a standout match in Liga MX.

Cruz Azul is confident after their qualification to the semifinals of the CONCACAF Champions League last Tuesday against América. Their subsequent goalless draw against America in the league brought them closer to securing a direct ticket to the upcoming Liguilla.

Meanwhile, León appears to be regaining form and achieving positive outcomes following a period of uncertainty, particularly after confirming its withdrawal from the Club World Cup. The felines now seem focused on one goal: winning the Liga MX campeonato.

For this match, our prediction is a 2-0 win for Cruz Azul.

Cruz Azul vs. León Betting Pick: Cruz Azul

Clausura MX 2025: Matchday 16: Monterrey x América

The Rayados endured a defeat against the Tigres in the recent Clasico Regio, resulting in two players, German Berterame and Oliver Torres, being handed red cards and subsequently ruled out for the upcoming match against the Aguilas.

Monterrey is ninth in the table, and they need two wins to secure a direct place in the Liguilla.

On the other hand, América, after their elimination against Cruz Azul in the CONCACAF Champions League, their subsequent match in the local league ended in a goalless draw, with no additional injuries for the team.

Las Águilas conceded first place in the table after accumulating only two wins in the last five matches. However, with a win, they ensure they finish inside the TOP 6 of the standings.

This upcoming match has significant championship importance as Coapa nears the end of the regular season and aims to finish strong to secure a high position in the tournament standings.

The game is expected to be highly competitive, given that both teams are coming off classic matches. They must deliver strong performances to continue their quest for the fourth title in Mexican soccer history and position themselves at the top of the league standings.

That said, our betting selection is a 1-0 win for America.

Monterrey vs. América Betting Pick: América

Clausura MX 2025: Matchday 16: San Luis vs. Toluca

Toluca is experiencing an exceptional period in the Clausura 2025, having managed 33 points in 15 games and securing first place in the Regular Phase standings. After the loss to América more than a month ago, they have since reeled off five consecutive wins, propelling them to the top of the league.

Currently, the Red Devils are close to reaching a significant achievement. Not only are they on track for the Primera División tournament in Mexico, but they are also on the verge of an achievement. If the team does not suffer a loss to Atletico San Luis in Matchday 16, they will secure qualification through the Annual Table for the 2026 Concachampions.

On the other hand, Atletico San Luis comes into this upcoming match with positive momentum after a 1-2 win against Tijuana in their previous clash. With one loss and three wins, they arrive into this stage with eight goals conceded and seven goals scored.

With Toluca potentially securing a spot in the Concachampions and Atletico San Luis showing resilience in recent matches, the upcoming encounter promises to be a compelling battle with high stakes to end the Clausura MX 2025 season.

For this match, our prediction is a comfortable 3-0 win for Toluca.

San Luis vs. Toluca Betting Pick: Toluca