San Francisco 49ers Betting Odds

Team Overview

The San Francisco 49ers are entering the 2024/2025 NFL season with high expectations and a strong desire to capture the elusive Super Bowl title. After a successful 2023 season that saw them finish with a 12-5 record and reach the Super Bowl, where they fell to the Kansas City Chiefs, the 49ers are poised to make another deep playoff run. Under the leadership of head coach Kyle Shanahan and general manager John Lynch, the team boasts a talented roster filled with playmakers on both sides of the ball. With a combination of veteran leadership and young talent, the 49ers are well-positioned to compete for the NFC title and aim for their first Super Bowl victory since 1994.

Offensive Line Analysis

The 49ers’ offensive line is a crucial component of their high-powered offense, anchored by All-Pro left tackle Trent Williams. Despite some struggles in pass protection last season, the line remains formidable, with key players like Aaron Banks and Jake Brendel providing stability in the interior. The addition of third-round draft pick Dominick Puni adds depth and versatility, potentially addressing some of the pass-blocking issues that arose during critical moments last year. This unit’s ability to protect quarterback Brock Purdy and open lanes for running back Christian McCaffrey will be vital for maintaining the team’s offensive efficiency, which ranked second in total offense last season.

Defensive Line Analysis

San Francisco’s defensive line remains one of the team’s strengths, despite the departure of several key contributors. The line is anchored by Defensive Player of the Year candidate Nick Bosa, who continues to be a dominant force off the edge. The addition of Leonard Floyd and Maliek Collins bolsters the pass rush, while Javon Hargrave provides a strong presence in the interior. Although the line has experienced some turnover, the core remains strong, and the 49ers have invested in depth to ensure continued success. The defensive line’s ability to pressure opposing quarterbacks and stop the run will be crucial in a division with potent offenses.

2024 NFL Season

Week 15 Review – Vs Los Angeles Rams

The San Francisco 49ers suffered a disappointing 12-6 loss to the Los Angeles Rams in Week 15 of the 2024 NFL season, dealing a significant blow to their playoff aspirations. This low-scoring affair, played on Thursday Night Football at Levi’s Stadium, was dominated by defense and field goals, with neither team managing to find the end zone. The 49ers’ usually potent offense struggled against a formidable Rams defense, managing only 14 receptions against nine pass breakups by the Rams’ secondary.

Despite the setback, there were some bright spots for the 49ers. The defense put up a valiant effort, holding the Rams to just four field goals and keeping the game within reach throughout. Linebacker Fred Warner continued his stellar play, leading the team in tackles and providing crucial run support. On offense, while struggling to find the end zone, the 49ers did manage to move the ball at times, with tight end George Kittle making several key receptions to keep drives alive.

This loss drops the 49ers to a precarious position in the playoff race, making their remaining games crucial for postseason hopes. Head coach Kyle Shanahan will need to regroup his team quickly as they prepare to face the Miami Dolphins in their next matchup. The 49ers will need to address their offensive struggles and find ways to convert drives into touchdowns if they hope to secure a playoff berth. Despite this setback, the team’s resilience throughout the season suggests they have the potential to bounce back and finish the regular season strong.

Week 14 Review – Vs Chicago Bears

The San Francisco 49ers snapped their three-game losing streak with a dominant 38-13 victory over the Chicago Bears in Week 14 of the 2024 NFL season at Levi’s Stadium. Quarterback Brock Purdy led the 49ers’ offensive onslaught, completing 20 of 25 passes for 325 yards and two touchdowns. Purdy’s precision was evident as he connected with wide receiver Jauan Jennings for both touchdown passes, with Jennings finishing the game with six receptions for 90 yards.

The 49ers’ ground game was equally impressive, despite injuries in their backfield. Running back Isaac Guerendo stepped up admirably, rushing for 78 yards and two touchdowns on 15 carries while also contributing 50 receiving yards. Tight end George Kittle delivered a standout performance, catching all six of his targets for 151 yards, with an impressive 103 yards coming after the catch. Kittle’s exceptional play earned him the highest grade of the game at 95.4, showcasing his ability to create mismatches and generate significant yardage after receptions.

San Francisco’s defense was equally dominant, stifling the Bears’ offense throughout the game. They held Chicago to a mere 162 total yards and sacked rookie quarterback Caleb Williams seven times. This defensive masterclass effectively neutralized any attempts by the Bears to mount a comeback. The comprehensive victory not only ended the 49ers’ losing streak but also reinforced their position as a formidable force in the NFC, improving their record and boosting their playoff aspirations as the regular season enters its final stretch.

Week 13 Review – Vs Buffalo Bills

The San Francisco 49ers suffered a devastating 35-10 loss to the Buffalo Bills in Week 13, dropping their record to 5-7 and severely damaging their playoff hopes. Quarterback Brock Purdy struggled in the harsh winter conditions, completing just 11 of 18 passes for 86 yards with no touchdowns and facing constant pressure from the Bills’ defense. The 49ers’ offense was further hampered by the early exit of star running back Christian McCaffrey, who left the game in the second quarter with a potential season-ending PCL injury.

Defensively, the 49ers were unable to contain the Bills’ potent offense, allowing 372 total yards and five touchdowns. Josh Allen proved to be a nightmare for San Francisco’s defense, recording touchdowns through passing, rushing, and even receiving. The 49ers’ typically stout run defense faltered, giving up 220 rushing yards to the Bills, including a 65-yard touchdown run by James Cook. The defense also failed to generate any turnovers, while the offense coughed up the ball three times.

Despite the lopsided score, there were a few bright spots for the 49ers. Guard Dominick Puni earned the highest PFF grade of the game at 92.4, showcasing his solid performance on the offensive line. Wide receiver Jauan Jennings led the team in receiving with 3 catches for 56 yards. However, these individual efforts were not enough to overcome the team’s overall struggles in the snowy conditions at Highmark Stadium. The 49ers now face an uphill battle to salvage their season and will need to regroup quickly to keep their dwindling playoff hopes alive. Looking ahead, the 49ers will face the Chicago Bears in Week 14, a crucial game that could make or break their season as they attempt to bounce back from this disappointing performance.

Week 12 Review – Vs Green Bay Packers

The San Francisco 49ers suffered a crushing 38-10 defeat at the hands of the Green Bay Packers in Week 12 of the 2024 NFL season. The absence of key players, including quarterback Brock Purdy, edge defender Nick Bosa, and offensive tackle Trent Williams, proved to be a significant hurdle for the 49ers. Their offense struggled to find its footing, with Brandon Allen likely stepping in for the injured Purdy. The lone bright spot was tight end George Kittle, who managed to earn an impressive 89.4 PFF grade despite the team’s overall poor performance.

Defensively, the 49ers were unable to contain the Packers’ offensive onslaught. Green Bay running back Josh Jacobs was particularly effective, scoring three touchdowns and forcing an astounding 11 missed tackles. Jacobs’ performance, which included 105 rushing yards with 81 coming after contact, was a key factor in the Packers’ dominant victory. The usually stout San Francisco defense crumbled under the relentless attack, highlighting the impact of injuries on both sides of the ball.

The 49ers face a critical matchup against the Buffalo Bills in Week 13. 

Week 11 Review – Vs Seattle Seahawks

The San Francisco 49ers suffered a heartbreaking 20-17 loss to the Seattle Seahawks in Week 11, snapping their three-season winning streak against their division rivals. This defeat was a significant setback for the 49ers, who had been riding high on a string of impressive performances. The game came down to the wire, with the Seahawks scoring the go-ahead touchdown in the final seconds, leaving San Francisco little time to respond.

Brock Purdy had a challenging day, managing only 160 passing yards and throwing an interception. The absence of Nick Bosa for a significant portion of the game due to injury was keenly felt, as the 49ers’ defense struggled to contain Geno Smith and the Seahawks’ offense in crucial moments. The usually potent 49ers offense found itself stifled, unable to establish its typical rhythm and dominance.

Despite the loss, the 49ers remain a formidable force in the NFC West. They’ll look to bounce back in Week 12 as they travel to face the Green Bay Packers at Lambeau Field.

Week 10 Review – Vs Tampa Bay Buccaneers

The San Francisco 49ers secured a hard-fought 23-20 victory over the Tampa Bay Buccaneers in Week 10, improving their record to 5-4 and keeping their playoff hopes alive. Quarterback Brock Purdy had an impressive outing, throwing for 353 yards, while the return of star running back Christian McCaffrey from an Achilles injury provided a significant boost to the offense. McCaffrey made an immediate impact, tallying 107 total yards and helping the 49ers achieve 0.199 EPA per play.

Tight end George Kittle continued to be a key playmaker, making several crucial catches including a spectacular touchdown reception that gave San Francisco the lead late in the game. On the defensive side, the 49ers contained the Buccaneers’ offense, allowing only -0.136 EPA per play and 3.8 yards per play. Defensive end Nick Bosa, despite dealing with a hip injury, came through with some crucial plays late in the game, including a key sack.

The 49ers will look to build on this momentum as they prepare to face their division rivals, the Seattle Seahawks, in Week 11.

Week 8 Review – Vs Dallas Cowboys

The San Francisco 49ers bounced back from their Week 7 loss with a 30-24 victory over the Dallas Cowboys in Week 8 of the 2024 NFL season. The game took place on October 27, 2024, at Levi’s Stadium in Santa Clara, California, showcasing a tale of two halves and a nail-biting finish.

Brock Purdy led the 49ers’ offense, overcoming a shaky first half to guide the team to a strong performance in the third quarter. Purdy finished the game completing 18 of 26 passes for 260 yards and a touchdown. The 49ers turned a 10-6 halftime deficit into a commanding 27-10 lead with three consecutive touchdown drives in the third quarter. George Kittle had an outstanding performance on National Tight Ends’ Day, catching six passes for 128 yards and a touchdown

the 49ers will have a bye week to rest and prepare for their upcoming matchup. They will return to action on November 10 for a road game against the Tampa Bay Buccaneers

Week 7 Review – Vs Kansas City Chiefs

The San Francisco 49ers fell to the Kansas City Chiefs 28-18. This matchup marked the fifth meeting between these teams during the Kyle Shanahan-John Lynch era. The loss dropped the 49ers’ record to 3-4 for the season.

Injuries significantly impacted the 49ers’ offensive production, with the team losing their top three receivers by the end of the game. Despite these setbacks, the 49ers’ defense kept them competitive for most of the contest. The 49ers led 14-6 at halftime, but the Chiefs’ offense found its stride in the fourth quarter, scoring two touchdowns that ultimately sealed the game.

The 49ers will face the Dallas Cowboys in their next game at Levi’s Stadium.

Week 6 Review – Vs Seattle Seahawks

The San Francisco 49ers emerged victorious in their Week 6 clash against the Seattle Seahawks, securing a convincing 36-24 win at Lumen Field.

Quarterback Brock Purdy continued his impressive 2024 campaign, throwing for 255 yards and three touchdowns. The 49ers’ offense showcased its explosive potential, with Deebo Samuel delivering a highlight-reel 76-yard catch-and-run touchdown and finishing the game with 102 receiving yards. The defense also stifled Seattle’s ground game, holding them to just 52 yards on 20 carries. However, the victory came at a cost, as running back Jordan Mason left the game with a shoulder injury, while cornerback Charvarius Ward was a late scratch due to a bruised knee.

The 49ers will face a formidable opponent in the Kansas City Chiefs. at Levi’s Stadium in Santa Clara, California. 

Week 5 Review – Vs Arizona Cardinals

The San Francisco 49ers suffered a disappointing 24-23 loss to the Arizona Cardinals at Levi’s Stadium this past Sunday.

Brandon Aiyuk had his best performance of the season, showcasing why the team invested in him with a big contract extension. The defense, usually a strength for the 49ers, struggled to contain Kyler Murray and the Cardinals’ offense in the second half.

Looking ahead, the 49ers face a short week as they prepare to travel to Seattle for a Thursday night divisional matchup against the Seahawks. 

Week 4 Review – Vs New England Patriots

The San Francisco 49ers bounced back from their two-game losing streak with a convincing 30-13 victory over the New England Patriots in Week 4 at Levi’s Stadium, improving their record to 2-2 for the season. Quarterback Brock Purdy had a solid outing, throwing for 288 yards and a touchdown. The highlight of his performance was a spectacular touchdown pass to George Kittle, who made an impressive catch between three defenders

Running back Jordan Mason stepped up in Christian McCaffrey’s absence, rushing for 123 yards and scoring a touchdown. Mason’s performance was crucial, as he accumulated 160 total yards, helping the 49ers control the game.

While the victory was crucial, the 49ers did suffer some injuries, including to Fred Warner, who left the game in the first half with an ankle injury. The team will be monitoring these injuries closely as they prepare to host the Arizona Cardinals in Week 5.

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Week 3 Review – Vs Los Angeles Rams

The San Francisco 49ers suffered a heartbreaking 27-24 loss to the Los Angeles Rams in Week 3 at SoFi Stadium, squandering a 14-point lead in the second half. Despite missing key offensive weapons like Christian McCaffrey, Deebo Samuel, and George Kittle, the 49ers managed to build a significant lead. Jauan Jennings had a career day, catching 11 passes for 175 yards and three touchdowns, while Brock Purdy passed for 292 yards and three touchdowns.

However, the 49ers’ defense struggled to contain the Rams’ offense, especially in the fourth quarter. Critical moments in the final minutes sealed their fate, including a missed 55-yard field goal attempt by Jake Moody with 2:43 left and a dropped pass by Ronnie Bell that could have put San Francisco in field goal range. A 25-yard pass interference penalty against De’Vondre Campbell ultimately put the Rams in position for the game-winning field goal.

Looking ahead to Week 4, the San Francisco 49ers will face the New England Patriots at Levi’s Stadium. This home game presents an opportunity for the 49ers to bounce back from their disappointing loss and improve their 1-2 record.

Week 2 Review – Vs. Minnesota Vikings

The San Francisco 49ers suffered their first loss of the 2024 season, falling to the Minnesota Vikings 23-17 in a hard-fought Week 2 matchup at U.S. Bank Stadium. Quarterback Brock Purdy struggled, completing 17 of 26 passes for 268 yards with no touchdowns and two interceptions. The 49ers’ offense was hampered by the absence of star running back Christian McCaffrey, who was placed on injured reserve prior to the game due to calf tightness and Achilles tendinitis.

Despite the loss, there were some bright spots for San Francisco. Linebacker Fred Warner put on a dominant performance, making impactful plays in all facets of the game. He recorded five defensive stops against the run, intercepted a pass, broke up another, and forced two fumbles. Wide receiver Brandon Aiyuk had a productive day, catching 7 passes for 108 yards. However, the 49ers’ offense struggled in the red zone, converting only 2 of 4 opportunities into touchdowns.

The 49ers will look to bounce back in Week 3 as they face their division rivals, the Los Angeles Rams, at SoFi Stadium. Both teams are dealing with significant injury concerns heading into the matchup. The 49ers will continue to be without McCaffrey, while the Rams are missing key receivers Puka Nacua and Cooper Kupp. This divisional clash will be crucial for both teams as they navigate their early-season challenges and vie for position in the competitive NFC West.

Week 1 Review – vs. New York Jets

The San Francisco 49ers opened the 2024 season with a commanding 32-19 victory over the New York Jets on Monday Night Football. Despite being without star running back Christian McCaffrey, the 49ers showcased their depth, with Jordan Mason leading the charge by rushing for 147 yards and a touchdown. Brock Purdy had a solid performance, completing 19-of-29 passes for 231 yards, while kicker Jake Moody was instrumental, hitting six field goals to secure the win.

Aaron Rodgers made his return for the Jets after last season’s Achilles injury but struggled to find rhythm. He threw for 167 yards, a touchdown, and an interception. While he connected with Allen Lazard for a 36-yard touchdown, the Jets couldn’t keep pace with the 49ers’ well-balanced attack. A late score in the final minute, with Tyrod Taylor stepping in for Rodgers, wasn’t enough to mount a comeback.

Next up for the 49ers is a clash with the Minnesota Vikings. After a dominant showing against the Jets, the 49ers will look to keep their momentum going as they prepare for their Week 2 matchup.

Odds to Win Division and Super Bowl

– Odds to Win NFC West: The 49ers are favorites to win the division, reflecting their strong roster and recent success.

– Odds to Win Super Bowl: +625, positioning them as one of the top contenders for the championship[2][4].

Predictions

– Overall Record: The 49ers are projected to finish with a 12-5 record, matching last year’s performance, given their talented roster and favorable odds.

– Playoff Chances: With their current odds, the 49ers are highly likely to make the playoffs and are expected to secure a high seed.

– Super Bowl Chances: The 49ers are considered legitimate contenders for a Super Bowl run, with their odds indicating a strong possibility of reaching the championship game.

In summary, the San Francisco 49ers are entering the 2024/2025 season with confidence and a well-rounded roster capable of competing at the highest level. With Brock Purdy leading the offense and a formidable defense, the 49ers are poised to be a formidable force in the NFC. As they aim to return to the Super Bowl, the 49ers are set to make a significant impact in the NFL landscape.Mason stepped up in Christian McCaffrey’s absence, rushing for 123 yards and scoring a touchdown