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49ers vs. Cardinals Betting Odds and Preview

Last Updated on September 29, 2023 5:32 pm by Erwin Noguera

The fourth week of the NFL features an important duel in the Western Division of the National Conference when the 49ers take on the Arizona Cardinals in San Francisco.

The 49ers are coming off a 30-12 win over the New York Giants, with a great game from the brilliant Brock Purdy, with 310 yards and two touchdown passes.

The Cardinals beat the Dallas Cowboys 28-16 at home, with an outstanding performance by quarterback Joshua Dobbs. 


Sunday, October 1 – 4:25 pm ET at the Levi’s Stadium

Moneyline odds:

49ers -950 

Cardinals +625

Where Can I Watch it?

Fox and NFL Game Pass on DAZN

Why Bet on the 49ers?

The 3 and 0 are the magic numbers for the San Francisco 49ers so far this season, as it is their current record and the points they have scored in the three games they have had (30).

The California franchise is coming off a 30-12 victory over the New York Giants, with a solid performance by quarterback Brock Purdy, who gained 310 yards, completed 25 of 37 passes, and was good for two touchdowns. He even attempted two carries. 

The most impressive thing is that this was achieved without the injured wide receiver, Brandon Aiyuk, which shows a clear offensive power that puts all the defensive structures in the NFL in fear.

Christian McCaffrey had 18 carries in the last game, with one touchdown, while Deebo Samuel ran for 129 yards, with an average of 21.5. In addition, Talanoa Hufanga intercepted a ball defensively.

San Francisco will have three straight games at home, which they will have to consolidate with victories to maintain their first place in the division and confirm that they are a great candidate to reach the Superbowl.

Why Bet on the Cardinals?

The Arizona Cardinals have a 1-2 record, but it could be said that to a certain extent, they are not a bad team, since all losses were close up to this point.

Their first win of the season came in their last home game, beating the Dallas Cowboys 28-16, a team that was coming into State Farm Stadium undefeated.

Joshua Dobbs has had the opportunity to start at quarterback and has not wasted his confidence, since in the last game he completed 17 of 21 passes, with 189 yards and one conversion.

In addition, James Conner and Rondale Moore had a great night in terms of carries, with 98 yards for the former and 54 for the latter. Both finished with a touchdown.

Arizona has had a good offensive effort so far and much of the work is due to offensive coordinator Drew Petzing. The team scored 28 points against the Giants and the same amount against Dallas.

Final Betting Analysis: 49ers vs. Cardinals

Two good teams will meet in San Francisco, where the 49ers are the great candidates to win, based on the superlative level of quarterback Brock Purdy at the helm of the offense and some defensive deficiencies of the opponent.

The numbers at have the 49ers as the favorite, as the Moneyline for them shows -950, meanwhile, the Cardinals have +625.

In January of this year, these teams played, and the victory went to the 49ers by 38-13, with three touchdown passes by Purdy. We believe this game will have a similar output, so go for a San Francisco victory and the over 43.5 at -110.

Go for a straight win for the 49ers Moneyline. If you bet $100 at -950, you will gain $10 for a total payout of $110.

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