Premier League Matchday 25 Betting Favorites

Last Updated on February 4, 2026 3:56 pm by Erwin Noguera

Matchday 25 of the 2025/26 Premier League season promises a thrilling set of encounters that could significantly influence both the title race and the battle for European qualification.

With only a handful of fixtures left before the end of the campaign, each game carries extra weight.

At the top, Arsenal seek to maintain their strong pace, while traditional heavyweights like Manchester City and Liverpool aim to close the gap and stay in the hunt. Meanwhile, the mid-table packs look to assert their position and avoid falling into the relegation zone.

At Gambyl Exchange, you can explore all the predictions for the Premier League, the final bets for this matchday, and the odds for each match.

Premier League Weekly Picks Betting Odds

Premier League Matchday 25: Manchester United vs. Tottenham Hotspur

Manchester United hosts Tottenham in what is expected to be a high-intensity clash at Old Trafford. Their 41 points and +8 goal difference reflect resilience, turning tight games into crucial results and showing improvement in defensive stability.

Tottenham, meanwhile, are in a different phase of the season, seeking consistency after a mixed run that has left them outside the top-half congestion. They are 14th on 29 points, having scored 35 goals and conceded 33. While Spurs boast attacking potential, their goal tally remains modest compared to United’s depth.

Manchester United vs. Tottenham Betting Pick: Manchester United

Premier League Matchday 25: Wolverhampton vs. Chelsea

This fixture pits contrasting fortunes: a Wolves side deep in the relegation battle with only 8 points against a Chelsea side pushing for European qualification. Wolves’ low point total highlights a season of difficulty, both in creating chances and defending at the back.

Chelsea’s campaign, by contrast, has been solid overall, with an attack capable of finding the net regularly and a defense that has conceded far fewer than many rivals. With a record of 11 wins, seven draws, and six losses, they hold 5th place and will look to exploit Wolves’ defensive struggles to build momentum among the upper table.

Wolves vs. Chelsea Betting Pick: Chelsea

Premier League Matchday 25: Liverpool vs. Manchester City

One of matchday 25’s most intriguing contests sees Liverpool host Manchester City at Anfield. Liverpool’s season has been turbulent, but a recent 4-1 win over Newcastle provided a morale-boosting performance, even as they remain in sixth on 39 points.

City, on the other hand, is second in the table on 47 points but has hit a recent rough patch with only one win in six matches, including a 2-2 draw with Tottenham. Manchester City’s title ambitions mean this away trip is critical not only for their hopes of catching Arsenal but also for maintaining confidence ahead of a run of crucial fixtures.

Liverpool vs. Manchester City Betting Pick: Manchester City

Premier League Matchday 25: Arsenal vs. Sunderland

Top-of-the-table Arsenal host Sunderland with a chance to strengthen their lead at the summit. Arsenal’s record of 16 wins, 5 draws, and 3 losses underscores a championship-calibre campaign, and their attacking output has been among the league’s best.

Sunderland, meanwhile, sit in tenth with 33 points. They have shown resilience and the ability to grind results, but lack the consistency to threaten title challengers regularly.

Arsenal’s recent win over Chelsea in the League Cup showcased their ability to manage tight matches and secure late goals in high-pressure situations, adding to their confidence. Sunderland will look to defend in numbers and exploit transitions, but their away form against elite opposition has been limited this season.

Arsenal vs. Sunderland Betting Pick: Arsenal